Professor, Department of Epidemiology, Graduate School of Public Health
Associate Director for Cancer Prevention and Population Sciences
Leader for the Cancer Epidemiology, Prevention and Control Program (CEPCP)
University of Pittsburgh Cancer Institute
University of Pittsburgh Medical Center (Shadyside) Cancer Pavilion
5150 Centre Avenue - Suite 4C
Pittsburgh, PA 15232
Phone: 412-864-7889
Fax: 412-623-3303
E-mail: yuanj@upmc.edu

Grants Assistant/Office Administrator
Brooke Curry Spencer
Cancer Epidemiology, Prevention and Control Program (CEPCP)
University of Pittsburgh Cancer Institute
University of Pittsburgh Medical Center (Shadyside) Cancer Pavilion
5150 Centre Avenue - Suite 4C
Pittsburgh, PA 15232
Phone: (412) 864-7861
Fax: (412) 623-3303
email: spencerbd@upmc.edu


Research Interests

• Environmental exposure and gene-environmental interaction in the etiology of cancer
• Biomarkers in relation to the development of cancer and risk prediction of cancer
• Chemopreventive effect of dietary agents for primary prevention of cancer
• Health outcomes and prognosis of cancer patients after behavior changes

Research Support

Principal Investigator


• 01/15/2010-12/31/2014
  Prospective Studies of Cancer Etiology and Prevention in Shanghai and Singapore
  National Institutes of Health (NIH)/National Cancer Institute (NCI)



• 07/01/2009-06/30/2014
  Biomarkers of NNK in Prediction of Lung Cancer Development in Smokers
  National Institutes of Health (NIH)/National Cancer Institute (NCI)



• 04/01/2008-02/28/2013
  Randomized Trial of PEITC as a Modifier of NNK Metabolism in Smokers
  National Institutes of Health (NIH)/National Cancer Institute (NCI)


Co-Principal Investigator (Subaward):


• 09/23/2008-07/31/2013
  Green Tea and Reduction of Breast Cancer Risk
  National Institutes of Health (NIH)/National Cancer Institute (NCI)



• 03/01/2009-02/28/2014
  Genetic and Environmental Determinants of Type 2 Diabetes in Chinese Singaporeans
  National Institutes of Health (NIH)/National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)



• 09/23/2011-08/31/2015
  NCI Cohort Consortium for One-Carbon Metabolism and Lung Cancer
  National Institutes of Health (NIH)/National Cancer Institute (NCI)



• 09/10/1997-07/31/2015
  Cancer Center Support Grant
  National Institutes of Health (NIH)/National Cancer Institute (NCI)
  [Program Leader, Cancer Epidemiology, Prevention & Control Program]

Education & Training

• Shanghai Medical University - MD, Medicine, 1983
• Shanghai Medical University - MPH, Public Health/Epidemiology, 1986
• University of Southern California - PhD, Epidemiology, 1996

Selected Publications

Refereed Articles (2009 - present)

1. Butler LM, Wang R, Koh W-P, Stern MC, Yuan J-M, Yu MC. Marine n-3 and saturated fatty acids in relation to risk of colorectal cancer in Singapore Chinese: a prospective study. Int J Cancer 124:678-686, 2009. [PMC2736597]



2. Yuan J-M, Ambinder A, Fan Y, Gao Y-T, Yu MC, Groopman JD. Prospective evaluation of hepatitis B 1762T/1764A mutations on hepatocellular carcinoma development in Shanghai, China. Cancer Epidemiol Biomarkers Prev 18:590-594, 2009. [PMC2640440]



3. Jiang X, Castelao JE, Groshen S, Cortessis VK, Shibata D, Conti DV, Yuan J-M, Pike MC, Gago-Dominguez M. Urinary tract infections and reduced risk of bladder cancer in Los Angeles. Br J Cancer 100:834-839, 2009. [PMC2653778]



4. Ognjanovic S, Yuan J-M, Chaptman A, Fan Y, Yu MC. Genetic polymorphisms in the cytokine genes and risk of hepatocellular carcinoma in low-risk non-Asians of United States. Carcinogenesis 30:758-762, 2009. [PMC2675648]



5. Yuan J-M, Koh WP, Murphy SE, Fan Y, Wang R, Carmella SG, Han S, Wickham K, Gao YT, Yu MC, Hecht SS. Urinary levels of tobacco-specific nitrosamine metabolites in relation to lung cancer development in two prospective cohorts of cigarette smokers. Cancer Res 69:2990-2995, 2009. [PMC2664854]



6. Koh W-P, Wu AH, Wang R, Ang L-W, Heng D, Yuan J-M, Yu MC. Gender specific associations between soy and risk of hip fracture in the Singapore Chinese Health Study. Am J Epidemiol 170:901-909, 2009. [PMC2664854]



7. Stern MC, Lin J, Figueroa JD, Yuan J-M, Xiang X-Y, Corral R, Joshi A, Rothman N, Kogevinas M, Malats N, Silverman D, Chanock S, Real P, Wu X, Kelsey K, Karagas M, Kiltie AE, Bishop DT, Sak SC, Choudhury A, Barrett JH, Elliot F, Vineis P, Sacerdote C, Guarrera S, Polidoro S, Allione A, Matullo G, Fletcher A, Benhamou S, Taylor JA, Placidi D, Porru S, Carta A, Campagna M, Arici C, Zhang Z-F, Steineck G, Garcia-Closas M. Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the International Consortium of Bladder Cancer. Cancer Res 69:6857-6864, 2009. [PMC2782435]



8. Moy KA, Yuan J-M, Chung F-L, Wang X-L, Van Den Berg D, Wang R, Gao Y-T, Yu MC. Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms and gastric cancer risk: a prospective study of men in Shanghai, China. Int J Cancer 125:2652-2659, 2009. [PMC2757456]



9. Stern MC, Van Den Berg D, Yuan J-M, Conti D, Gago-Dominguez M, Pike MC, Xiang Y-B, Gao Y-T, Cortessis VK. Sequence variant on 3q28 and urinary bladder cancer risk: findings from the Los Angeles-Shanghai Bladder Case-Control Study. Cancer Epidemiol Biomarkers Prev 18:3057-3061, 2009. [PMC2783174]



10. Stern MC, Butler LM, Corral R, Joshi AD, Yuan J-M, Koh WP, Yu MC. Polyunsaturated fatty acids, DNA repair single nucleotide polymorphisms and colorectal cancer in the Singapore Chinese Health Study. J Nutrigenet Nutrigenomics 2:273-279, 2009. [PMC2941837]



11. Peterson S, Yuan J-M, Koh W-P, Sun C-L, Wang R, Turesky RJ, Yu MC. Coffee intake and risk of colorectal cancer among Chinese in Singapore: the Singapore Chinese Health Study. Nutr Cancer 62:21-29, 2010. [PubMed - Indexed for MEDLINE]



12. Koh W-P, Yuan J-M, Wang R, Lee H-P, Yu MC. Body mass index and smoking-related lung cancer risk in the Singapore Chinese Health Study. Br J Cancer 102:610-614, 2010. [PMC2822936]



13. Mueller NT, Odegaard A, Anderson A, Yuan J-M, Gross M, Koh W-P, Pereira MA. Soft drink and juice consumption and risk of pancreatic cancer: the Singapore Chinese Health Study. Cancer Epidemiol Biomarkers Prev 19:447-455, 2010. [PubMed - Indexed for MEDLINE]



14. Butler LM, Wu AH, Wang R, Koh W-P, Yuan J-M, Yu MC. A vegetable-fruit-soy dietary pattern protects against breast cancer among postmenopausal Singapore Chinese. Am J Clin Nutr 91:1013-1019, 2010. [PMC2844682]



15. Inoue-Choi M, Yuan J-M, Yang CS, Van Den Berg DJ, Lee M-J, Gao Y-T, Yu MC. Genetic association between the COMT genotype and urinary levels of tea polyphenols and their mebolites among daily green tea drinkers. Int J Mol Epidemiol Genet (IJMEG) 1:114-123, 2010. [PMC3010377]



16. Hecht SS, Seow S, Wang M, Wang R, Meng L, Koh W-P, Carmella SG, Chen M, Han S, Yu MC, Yuan J-M. Elevated levels of volatile organic carcinogen and toxicant biomarkers in Chinese women who regularly cook at home. Cancer Epidemiol Biomarkers Prev 19:1185-1192, 2010. [PMC2866160]



17. Butler LM, Wong AS, Koh W-P, Wang R, Yuan J-M, Yu MC. Calcium intake increases risk of prostate cancer among Singapore Chinese. Cancer Res 70:4941-4948, 2010. [NIHMS200268]



18. Koh WP, Wang R, Ang LW, Heng D, Yuan J-M, Yu MC. Diabetes and risk of hip fracture in the Singapore Chinese Health Study. Diabetes Care 33:1766-70, 2010. [PMC2909059]



19. Abnet CC, Freedman ND, Hu N, Wang Z, Yu K, Shu XO, Yuan J-M, Zheng W, Dawsey SM, Dong LM, Lee MP, Ding T, Qiao YL, Gao YT, Koh WP, Xiang YB, Tang ZZ, Fan JH, Wang C, Wheeler W, Gail MH, Yeager M, Yuenger J, Hutchinson A, Jacobs KB, Giffen CA, Burdett L, Fraumeni JF, Jr., Tucker MA, Chow WH, Goldstein AM, Chanock SJ, Taylor PR. A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma. Nat Genet 42:764-767, 2010. [PMC2947317]



20. Rothman N, Garcia-Closas M, Chatterjee N, Malats N, Wu X, Figueroa JD, Real FX, Van Den Berg D, Matullo G, Baris D, Thun M, Kiemeney LA, Vineis P, De Vivo I, Albanes D, Purdue MP, Rafnar T, Hildebrandt MA, Kiltie AE, Cussenot O, Golka K, Kumar R, Taylor JA, Mayordomo JI, Jacobs KB, Kogevinas M, Hutchinson A, Wang Z, Fu YP, Prokunina-Olsson L, Burdett L, Yeager M, Wheeler W, Tardon A, Serra C, Carrato A, Garcia-Closas R, Lloreta J, Johnson A, Schwenn M, Karagas MR, Schned A, Andriole G, Jr., Grubb R, 3rd, Black A, Jacobs EJ, Diver WR, Gapstur SM, Weinstein SJ, Virtamo J, Cortessis VK, Gago-Dominguez M, Pike MC, Stern MC, Yuan J-M, Hunter DJ, McGrath M, Dinney CP, Czerniak B, Chen M, Yang H, Vermeulen SH, Aben KK, Witjes JA, Makkinje RR, Sulem P, Besenbacher S, Stefansson K, Riboli E, Brennan P, Panico S, Navarro C, Allen NE, Bueno-de-Mesquita HB, Trichopoulos D, Caporaso N, Landi MT, Canzian F, Ljungberg B, Tjonneland A, Clavel-Chapelon F, Bishop DT, Teo MT, Knowles MA, Guarrera S, Polidoro S, Ricceri F, Sacerdote C, Allione A, Cancel-Tassin G, Selinski S, Hengstler JG, Dietrich H, Fletcher T, Rudnai P, Gurzau E, Koppova K, Bolick SC, Godfrey A, Xu Z, Sanz-Velez JI, M DG-P, Sanchez M, Valdivia G, Porru S, Benhamou S, Hoover RN, Fraumeni JF, Jr., Silverman DT, Chanock SJ. A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. Nat Genet 42:978-984, 2010. [PMC3049891]



21. Moy KA, Fan Y, Wang R, Gao YT, Yu MC, Yuan J-M. Alcohol and tobacco use in relation to gastric cancer: a prospective study of men in Shanghai, China. Cancer Epidemiol Biomarkers Prev 19:2287-2297, 2010. [PMC2936659]



22. Jiang X, Castelao JE, Yuan J-M, Groshen S, Stern MC, Conti DV, Cortessis VK, Coetzee GA, Pike MC, Gago-Dominguez M. Hypertension, diuretics and antihypertensives in relation to bladder cancer. Carcinogenesis 31:1964-1971, 2010. [PMC2966553]



23. Odegaard AO, Koh W-P, Gross M, Duval S, Yu MC, Yuan J-M, Pereira MA. BMI, all-cause and cause-specific mortality in Chinese Singaporean men and women: the Singapore Chinese Health Study. PLoS One 5:e14000, 2010. [PMC2981556]



24. Cortessis VK, Yuan J-M, Van Den Berg D, Jiang X, Gago-Dominguez M, Stern MC, Castelao JE, Xiang YB, Gao YT, Pike MC, Conti DV. Risk of urinary bladder cancer is associated with 8q24 variant rs9642880[T] in multiple racial/ethnic groups: results from the Los Angeles-Shanghai case-control study. Cancer Epidemiol Biomarkers Prev 19:3150-3156, 2010. [PubMed - Indexed for MEDLINE]



25. Tao L, Xiang YB, Wang R, Nelson HH, Gao YT, Chan KK, Yu MC, Yuan J-M. Environmental tobacco smoke in relation to bladder cancer risk - the Shanghai Bladder Cancer Study. Cancer Epidemiol Biomarkers Prev 19:3087-3095, 2010. [PMC3003610]



26. Hecht SS, Yuan J-M, Hatsukami D. Applying tobacco carcinogen and toxicant biomarkers in product regulation and cancer prevention. Chem Res Toxicology 23:1001-1008, 2010. [PMC2891118]



27. Gago-Dominguez M, Jiang X, Conti DV, Castelao E, Stern MC, Cortessis VK, Pike MC, Xiang Y-B, Gao Y-T, Yuan J-M, Van Den Berg D. Genetic variations on chromosomes 5p15 and 15q25 and bladder cancer risk: findings from the Los Angeles-Shanghai Bladder Case-Control Study. Carcinogenesis 32:197-202, 2011. [PMC3026841]



28. Zheng W, McLerran DF, Rolland B, Zhang X, Inoue M, Matsuo K, He J, Gupta PC, Ramadas K, Tsugane S, Irie F, Tamakoshi A, Gao YT, Wang R, Shu XO, Tsuji I, Kuriyama S, Tanaka H, Satoh H, Chen CJ, Yuan J-M, Yoo KY, Ahsan H, Pan WH, Gu D, Pednekar MS, Sauvaget C, Sasazuki S, Sairenchi T, Yang G, Xiang YB, Nagai M, Suzuki T, Nishino Y, You SL, Koh WP, Park SK, Chen Y, Shen CY, Thornquist M, Feng Z, Kang D, Boffetta P, Potter JD. Association between body-mass index and risk of death in more than 1 million Asians. N Engl J Med 364:719-729, 2011. [PubMed - Indexed for MEDLINE]



29. Odegaard AO, Koh W-K, Butler LM, Duval S, Gross MD, Yu MC, Yuan J-M, Pereira MA. Dietary patterns and incident type 2 diabetes in Chinese men and women: The Singapore Chinese Health Study. Diabetes Care 34:880-885, 2011. [PMC3064045]



30. Johnson S, Koh W-P, Wang R, Govindarajan S, Yu MC, Yuan J-M. Coffee consumption and reduced risk of hepatocellular carcinoma: Findings from the Singapore Chinese Health Study. Cancer Causes Control 22:503-510, 2011. [PubMed - Indexed for MEDLINE]



31. Brostow DP, Odegaard AO, Koh W-P, Duval S, Gross MD, Yuan J-M, Pereira MA. Omega-3 fatty acids and incident type 2 diabetes: The Singapore Chinese Health Study. Am J Clin Nutr 94:520-626, 2011. [PMC3142726]



32. Odegaard AO, Koh W-P, Yu MC, Yuan J-M. Body mass index and risk of colorectal cancer in Chinese Singaporeans: the Singapore Chinese Health Study. Cancer 117:3841-3849, 2011. [PMC3151024]



33. Koh W-P, Yuan J-M, Wang R, Govindarajan S, Oppenheimer R, Zhang Z-Q, Yu MC, Ingles SA. Aromatase (CYP19) promoter gene polymorphism and risk of nonviral hepatitis-related hepatocellular carcinoma. Cancer 117: 3383-92, 2011. [PMC3138892]



34. Koh WP, Robien K, Wang R, Govindarajan S, Yuan J-M, Yu MC. Smoking as an independent risk factor for hepatocellular carcinoma: The Singapore Chinese Health Study. Br J Cancer 105:1430-1435, 2011. [PMC3241540]



35. Koh W-P, Yuan J-M, Wang R, Lee Y-P, Lee B-L, Yu MC, Ong C-N. Plasma carotenoids and risk of acute myocardial infarction in the Singapore Chinese Health Study. Nutr Metab Cardiovascular Dis 21:685-90, 2011 [PMC2891412]



36. Koh W-P, Van Den Berg D, Jin A, Wang R, Yuan J-M, Yu MC. Combined effects of MDM2 SNP309 and TP53 R72P polymorphisms, and soy isoflavones on breast cancer risk among Chinese women in Singapore. Breast Cancer Res Treat 130: 1011-9, 2011. [PubMed - In process]



37. Yuan J-M, Gao Y-T, Murphy SE, Carmella SG, Wang R, Zhong Y, Moy KA, Davis AB, Tao L, Chen M, Han S, Nelson HH, Yu MC, Hecht SS. Urinary levels of cigarette smoke constituent metabolites are prospectively associated with lung cancer development in smokers. Cancer Res 71:6749-57, 2011. [PubMed - Indexed for MEDLINE]



38. Odegaard AO, Koh W-P, Gross M, Yuan J-M, Pereira MA. Combined lifestyle factors and cardiovascular disease mortality in Chinese men and women: The Singapore Chinese Health Study. Circulation 124:2847-54, 2011. [PubMed - In Process]



39. Teng GG, Ang L-W, Saag K, Yu M, Yuan J-M, Koh W-P. Mortality due to coronary heart disease and kidney disease among middle-aged and elderly men and women with gout in the Singapore Chinese Health Study. Ann Rheum Dis Dec 15, 2011. [Epub ahead of print] [PubMed - as supplied by publisher]



40. Nauwelaers G, Bessette EE, Gu D, Fessard V, Yuan J-M, Yu MC, Langouët S, Turesky RJ. DNA adduct formation of 4-aminobiphenyl and heterocyclic aromatic amines in human hepatocytes. Chem Res Toxicol 24:913-25, 2011. [PMC3118939]



41. Boffetta P, McLerran D, Chen Y, Inoue M, Sinha R, He J, Gupta PC, Tsugane S, Irie F, Tamakoshi A, Gao Y-T, Shu X-O, Wang R, Tsuji I, Kuriyama S, Matsuo K, Satoh H, Chen C-J, Yuan J-M, Yoo K-Y, Ahsan H, Pan W-H, Gu D, Pednekar MS, Sasazuki S, Sairenchi T, Yang G, Xiang Y-B, Nagai M, Tanaka H, Nishino Y, You S-L, Koh W-P, Park S-K, Shen C-Y, Thornquist M, Kang D, Rolland B, Feng Z, Zheng W, Potter JD. Body mass index and diabetes in Asia: A cross-sectional pooled analysis of 900,000 individuals in the Asia Cohort Consortium. PLoS One 6:e19930, 2011. [PMC3120751]



42. Koh W-P, Nelson HH, Yuan J-M, Van den Berg D, Jin A, Wang R, Yu MC. Glutathione S-transferase (GST) gene polymorphisms, cigarette smoking and colorectal cancer risk among Chinese in Singapore. Carcinogenesis 32:1507-11, 2011. [PMC3179426]



43. Yuan J-M, Knezevich AD, Wang R, Gao Y-T, Hecht SS, Stepanov I. Urinary levels of the tobacco-specific carcinogen N?-nitrosonornicotine and its glucuronide are strongly associated with esophageal cancer risk in smokers. Carcinogenesis 32:1366-71, 2011. [PMC3202311]



44. Lim SH, Tai BC, Yuan JM, Yu MC, Koh WP. Smoking cessation and mortality among middle-aged and elderly Chinese in Singapore: the Singapore Chinese Health Study. Tob Control Dec 14, 2011. [Epub ahead of print] [PubMed - As supplied by publisher]



45. Mueller NT, Odegaard AO, Gross MD, Koh WP, Yu MC, Yuan JM, Pereira MA. Soy intake and risk of type 2 diabetes mellitus in Chinese Singaporeans. Soy intake and risk of type 2 diabetes. Eur J Nutr Nov 18, 2011. (Erratum Dec 11)[Epub ahead of print] [PubMed - As Supplied by Publisher]



46. Gu D, Turesky RJ, Tao Y, Langouët SA, Nauwelaërs GC, Yuan JM, Yee D, Yu MC. DNA adducts of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 4-aminobiphenyl are infrequently detected in human mammary tissue by liquid chromatography/tandem mass spectrometry. Carcinogenesis 33:124-30, 2012. [PMC3247154]



47. Cash HL, Tao L, Yuan J-M, Marsit CJ, Houseman EA, Xiang Y-B, Gao Y-T, Nelson HN, Kelsey KT. LINE-1 hypomethylation is associated with bladder cancer risk among non-smoking Chinese. Int J Cancer 130:1151-9, 2012 [PMC3208798]



48. Kensler TW, Ng D, Carmella SG, Chen M, Jacobson LP, Munoz A, Egner PA, Chen JG, Qian SG, Chen TY, Fahey JW, Talalay P, Groopman JD, Yuan J-M, Hecht SS. Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China. Carcinogenesis 2012 33(1):101-107. [PMC3276337]



49. Tao L, Xiang Y-B, Chan KK, Wang R, Gao Y-T, Yu MC, Yuan J-M. Cytochrome P4501A2 phenotype and bladder cancer risk: the Shanghai Bladder Cancer Study. Int J Cancer 130:1174-83, 2012. [PMC3167995]



50. Jiang X, Castelao JE, Yuan J-M, Stern MC, Conti DV, Cortessis VK, Pike MC, Gago-Dominguez M. Cigarette smoking and subtypes of bladder cancer. Int J Cancer 130:1174-83, 2012 [PMC3210924]



51. Oppeneer SJ, Ross JA, Koh W-P, Yuan J-M, Robien K. Genetic variation in folylpolyglutamate synthase and gamma-glutamyl hydrolase and plasma homocysteine levels in the Singapore Chinese Health Study. Mol Genet Metab 105:73-8, 2012. [PMC3253895]



52. Boffetta P, Hazelton WD, Chen Y, Sinha R, Inoue M, Gao YT, Koh WP, Shu XO, Grant EJ, Tsuji I, Nishino Y, You SL, Yoo KY, Yuan J-M, Kim J, Tsugane S, Yang G, Wang R, Xiang YB, Ozasa K, Nagai M, Kakizaki M, Chen CJ, Park SK, Shin A, Ahsan H, Qu CX, Lee JE, Thornquist M, Rolland B, Feng Z, Zheng W, Potter JD. Body mass, tobacco smoking, alcohol drinking and risk of cancer of the small intestine – a pooled analysis of over 500,000 subjects in the Asia Cohort Consortium. Ann Oncol 2011 Dec 6. [Epub ahead of print] [PubMed – as Supplied by Publisher]



53. Shamliyan TA, Johnson JR, MacDonald R, Shaukat A, Yuan J-M, Kane RL, Wilt TJ. Systematic review of the literature on comparative effectiveness of antiviral treatments for chronic hepatitis B infection. J Gen Intern Med 26:326-339, 2011. [PMC3043173]



54. Yuan J-M, Gao Y-T, Wang R, Chen M, Carmella SG, Hecht SS. Urinary levels of volatile organic carcinogen and toxicant biomarkers in relation to lung cancer development in smokers. Carcinogenesis 2012 Feb 21; doi: 10.1093/carcin/bgs026.



55. Lee E, Hsu C, Van den Berg D, Ursin G, Koh WP, Yuan J-M, Stram DO, Yu MC, Wu AH. Genetic variation in peroxisome proliferator-activated receptor gamma, soy, and mammographic density in Singapore Chinese women. Cancer Epidemiol Biomarkers Prev 2012 April;21(4):635-644. [PubMed – in process]



56. Abnet CC, Wang Z, Song X, Hu N, Zhou FY, Freedman ND, Li XM, Yu K, Shu XO, Yuan JM, Zheng W, Dawsey SM, Liao LM, Lee MP, Ding T, Qiao YL, Gao YT, Koh WP, Xiang YB, Tang ZZ, Fan JH, Chung CC, Wang C, Wheeler W, Yeager M, Yuenger J, Hutchinson A, Jacobs KB, Giffen CA, Burdett L, Fraumeni JF Jr, Tucker MA, Chow WH, Zhao XK, Li JM, Li AL, Sun LD, Wei W, Li JL, Zhang P, Li HL, Cui WY, Wang WP, Liu ZC, Yang X, Fu WJ, Cui JL, Lin HL, Zhu WL, Liu M, Chen X, Chen J, Guo L, Han JJ, Zhou SL, Huang J, Wu Y, Yuan C, Huang J, Ji AF, Kul JW, Fan ZM, Wang JP, Zhang DY, Zhang LQ, Zhang W, Chen YF, Ren JL, Li XM, Dong JC, Xing GL, Guo ZG, Yang JX, Mao YM, Yuan Y, Guo ET, Zhang W, Hou ZC, Liu J, Li Y, Tang S, Chang J, Peng XQ, Han M, Yin WL, Liu YL, Hu YL, Liu Y, Yang LQ, Zhu FG, Yang XF, Feng XS, Wang Z, Li Y, Gao SG, Liu HL, Yuan L, Jin Y, Zhang YR, Sheyhidin I, Li F, Chen BP, Ren SW, Liu B, Li D, Zhang GF, Yue WB, Feng CW, Qige Q, Zhao JT, Yang WJ, Lei GY, Chen LQ, Li EM, Xu LY, Wu ZY, Bao ZQ, Chen JL, Li XC, Zhuang X, Zhou YF, Zuo XB, Dong ZM, Wang LW, Fan XP, Wang J, Zhou Q, Ma GS, Zhang QX, Liu H, Jian XY, Lian SY, Wang JS, Chang FB, Lu CD, Miao JJ, Chen ZG, Wang R, Guo M, Fan ZL, Tao P, Liu TJ, Wei JC, Kong QP, Fan L, Wang XZ, Gao FS, Wang TY, Xie D, Wang L, Chen SQ, Yang WC, Hong JY, Wang L, Qiu SL, Goldstein AM, Yuan ZQ, Chanock SJ, Zhang XJ, Taylor PR, Wang LD. Genotypic variants at 2q33 and risk of esophageal squamous cell carcinoma in China: A meta-analysis of genome-wide association studies. Hum Mol Genet. 2012 May 1; 21(9):2132-41 [PubMed – in process]



57. Koh W-P, Ong C-N, Chen C, Yuan J-M, Lee YP, Naidoo N, Wang R, Hong L-S, Van Dam RM. Plasma vitamin E and coenzyme Q10 are not associated with a lower risk of acute myocardial infarction in Singapore Chinese adults. J Nutr, Accepted 06-Mar-2012, [PubMed - in process]



58. Lim V, Li J, Gong Y, Yuan J-M, Wu TS, Hammond J, Jin A, Koh W-P, Yong EL. Serum free estradiol and estrogen receptor-a mediated estrogenic activity are related to decreased incident hip fractures in older women. Bone, 2012 Jun 50(6):1311-6 [PubMed – in process]



59. Thyagarajan B, Wang R, Barcelo H, Koh W-P, Yuan J-M. Mitochondrial copy number is associated with colorectal cancer risk. Cancer Epidemiol Biomarkers Prev, Accepted 08-Mar-2012, in press.



60. Inoue-Choi M, Nelson HH, Robien K, Arning E, Bottiglieri T, Koh WP, Yuan J-M. One-carbon metabolism nutrient status and plasma S-adenosylmethionine concentrations in middle-aged and older Chinese in Singapore. Intl J Mol Epidemiol Genet, Accepted 18-Apr-2012, in press.



61. Robien K, Butler LM, Wang R, Koh W-P, Yuan J-M. Genetic and environmental predictors of serum 25-hydroxyvitamin D concentrations among middle-aged and elderly Chinese in Singapore. Br J Nutr 2012 May 15:1-10. [PubMed - as supplied by publisher]