Distinguished University Professor of Public Health
Department of Epidemiology
130 N. Bellefield Avenue, Room 550
Pittsburgh, PA 15213
Voice: (412) 383-1895
E-mail: kullerl@edc.pitt.edu

Research Interests

Epidemiology of CVD
Epidemiology of breast cancer
Epidemiology of aging
HIV and chronic diseases
Dementia
Preventive medicine
Rheumatoid arthritis and CVD

Research Support

Principal Investigator - Active


• Epidemiology of Cardiovascular Risk Factors in Women (1983-2012) NHLBI
• Cardiovascular Health Study Events Follow Up (2005-2010) University of Washington
• Clinical Trial/Observational Study of the Women's Health Initiative (WHI) (2005-2010) NHLBI
• Hormone Therapy, Estrogen Metabolism and Risk in the WHI (2007-2009) NHLBI
• Reduction of Triglycerides in Women on Hormone Therapy (2007-2009)
• Ginkgo Biloba Prevention Trial in Older Adults (2005-2010)
• Rheumatoid Arthritis and Risk of CVD and Total Mortality
• Epidemiology of Heterogeneity in type 2 Diabetes
• Epidemiology of Putative Genuine Genetic Variants: The WHI


Co-Principal Investigator


• Dynamic of Health, Aging and Body Composition (1996-2004) NIA
• Ginkgo Biloba Prevention Trial in Older Individuals (1999-2005) NCCAM


Co-Investigator


• CDC Prevention Research Center (Center for Healthy Aging) (2005-2009)
• Osteoporotic Fractures in Men (2006-2012)
• Epidemiology of CHD of Men Aged 40+ in US, Hawaii and Japan (2008-2012)
• Cardiovascular Disease in HIV Infected and Uninfected Veterans (2009-2011)
• Predictors of Alzheimers Disease in Mild Cognitive Impairment (2008-2012)

Education & Training

• Hamilton College - B.A., 1955
• George Washington University - M.D. Medicine, 1959
• Johns Hopkins University - M.P.H. Public Health, 1964
• Johns Hopkins University - Dr.P.H. Public Health, 1966

Recent Publications

Neuhaus J, Jacobs DR Jr, Baker JV, Calmy A, Duprez D, La Rosa A, Kuller LH, Pett SL, Ristola M, Ross MJ, Shlipak MG, Tracy R, Neaton JD, for the International Network for Strategic Initiatives in Global HIV Trials (INSIGHT) Strategies for Management of Anti-Retroviral Therapy (SMART), Multi-Ethnic Study of Atherosclerosis (MESA), and Coronary Artery Development in Young Adults (CARDIA) Research Group. Markers of inflammation, coagulation, and renal function are elevated in adults with HIV infection. J Infect Disability 2010;201:1788-1795. PMCID: PMC2872049

Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration. Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. Lancet 2010;375:1634-1639. PMCID: PMC2867029

Seshadri S, Fitzpatrick AL, Ikram MA, DeStafano AL, Gudnason V, Boada M, Bis JC, et al. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA 2010;303:1832-1840.

Choo J, Ueshima H, Curb JD, Shin C, Evans RW, El-Saed A, Kadawaki T, Okamura T, Nakata K, Otake T, Miura K, Abbott RD, Sutton-Tyrrell K, Edmundowicz D, Kuller LH, Sekikawa A for the ERA-JUMP Study Group. Serum n-6 fatty acids and lipoprotein subclasses in middle-aged men: the population-based cross-sectional ERA-JUMP Study. Am J Clin Nutr 2010;91:1195-1203. PMCID: PMC2854899

Robare JF, Milas NC, Bayles CM, Williams K, Newman AB, Lovalekar MT, Boudreau R, McTigue K, Albert SM, Kuller LH. The Key to Life Nutrition Program: results from a community-based dietary sodium reduction trial. Public Health Nutr 2010;13:606-614.

Brinkley TE, Lovato JF, Arnold AM, Furberg CD, Kuller LH, Burke GL, Nahin RL, Lopez OL, Williamson JD, for the Ginkgo Evaluation of Memory (GEM) StudyInvestigators. Am J Hypertens 2010;23:528-533.

Kuller LH. Does the Framingham Risk Score predict risk in women as well as it does in men? Curr Cardio Risk Rep 2010;4:229-236.

Thurston RC, Kuller LH, Edmundowicz D, Matthews KA. History of hot flashes and aortic calcification among postmenopausal women. Menopause 2010;17:256-261. PMCID: PMC2837097

Kuller LH, Lopez OL. Commentary on “Developing a national strategy to prevent dementia: Leon Thal Symposium 2009.” Is dementia among older individuals 75+ a unique disease? Alzheimers Dement 2010;6:142-144.

Barnes DE, Covinsky KE, Whitmer RA, Kuller LH, Lopez OL, Yaffe K. Commentary on “Developing a national strategy to prevent dementia: Leon Thal Symposium: 2009.” Dementia risk indices: A framework for identifying individuals with a high dementia risk. Alzheimers Dement 2010;6:138-141.

Khachaturian ZS, Barnes D, Einstein R, Johnson S, Lee V, Roses A, Sager MA, Shankle WR, Snyder PJ, Petersen RC, Schellenberg G, Trojanowski J, Aisen P, Albert MS, Breitner JCS, Buckholtz N, Carillo M, Ferris S, Greenberg BD, Grundman M, Khachaturian AS, Kuller LH, Lopez OL, Maruff P, Mohs RFC, Morrison-Bogorad M, Phelps C, Reiman E, Sabbagh M, Sano M, Schneider LS, Siemers E, Tariot P, Touchon J, Vellas B. Developing a national strategy to prevent dementia: Leon Thal Symposium 2009. Alzheimers Dement 2010;6:89-97.

Kuller LH, Margolis KL, Gaussoin SA, Bryan NR, Kerwin D, Limacher M, Wassertheil-Smoller S, Williamson J, Robinson JG, for the Women’s Health Initiative Memory Study Research Group. Relationship of hypertension, blood pressure, and blood pressure control with white matter abnormalities in the Women’s Health Initiative Memory Study (WHIMS)-MRI trial. J Clin Hypertens 2010;12:203-12. PMCID: PMC2864933

Mukamal KJ, Pai JK, O’Meara ES, Tracy RP, Psaty BM, Kuller LH, Newman AB, Yende S, Curhan GC, Siscovick DS, Rimm EB. CRP gene variation and risk of community-acquired pneumonia. Respirology 2010;15:160-164.

Patrick A, Bunker CH, Nelson JB, Wheeler WW, Zmuda JM, Richard JR, Belle AC, Kuller LH. Prostate-cancer screening in an Afro-Caribbean population: the Tobago Prostate Cancer Screening Study. BJU International 2010;105:745-746.

Rubin JP, Landfair AS, Shestak K, Lane D, Valoski A, Chang Y, Tindle HA, Kuller LH. Health characteristics of women with breast implants. Plast Reconstr Surg 2010;125:799-810. PMC2837521

Raji CA, Ho AJ, Parikshak NN, Becker JT, Lopez OL, Kuller LH, Hua X, Leow AD, Toga AW, Thompson PM. Brain structure and obesity. Hum Brain Mapp 2010;31:353-364. PMCID: PMC2826530

Kuller LH. Cardiovascular disease is preventable among women. Expert Rev Cardiovasc Ther 2010;8:175-187.

Barnes DE, Haight TJ, Mehta KM, Carlson MC, Kuller LH, Tager IB. Secondhand smoke, vascular disease, and dementia incidence: Findings from the Cardiovascular Health Cognition Study. Am J Epidemiol 2010;171:292-302.

Freiberg MS, McGinnis KA, Kraemer K, Samet JH, Conigliaro J, Ellison RC, Bryant K, KullerLH, Justice AC, for the VACS Project Team. The association between alcohol consumption and prevalent cardiovascular diseases among HIV-infected and HIV-uninfected men. J Acquir Immune Defic Syndr 2010;53:247-253. PMCID: PMC2858978

Wong ND, Lopez VA, Roberts CS, Solomon HA, Burke GL, Kuller L, Tracy R, Yanez D, Psaty BM. Combined association of lipids and blood pressure in relation to cardiovascular disease in the elderly: The Cardiovascular Health Study. Am J Hypertens 2010;23:161-167.

Kuller LH. Risk estimation in 2009. Circ Cardiovasc Qual Outcomes 2010;3:4-5.

Kuller LH, Ives DG, Fitzpatrick AL, Carlson Mc, Mercado C, Lopez OL, Burke GL, Furberg CD, DeKosky ST, for the Ginkgo Evaluation of Memory Study Investigators. Does Ginkgo biloba reduce the risk of cardiovascular events? Circ Cardiovasc Qual Outcomes 2010;3:41-47. PMCID: PMC2858335